Bassett C A, Schink-Ascani M
Bioelectric Research Center, Riverdale, New York 10463.
Calcif Tissue Int. 1991 Sep;49(3):216-20. doi: 10.1007/BF02556121.
Ninety-one patients with congenital pseudarthrosis of the tibia have been treated with pulsed electromagnetic fields (PEMFs) since 1973 and all except 4 followed to puberty. Lesions were stratified by roentgenographic appearance. Type I and type II had gaps less than 5 mm in width. Type III were atrophic, spindled, and had gaps in excess of 5 mm. Overall success in type I and II lesions was 43 of 60 (72%). Of those 28 patients seen before operative repair had been attempted, 7 of 8 type I lesions healed (88%), whereas 16 of 20 type II lesions healed (80%) on PEMFs and immobilization alone. Only 19% (6 of 31) type III lesions united, only one of which did not require surgery. Sixteen of 91 limbs (18%) were ultimately amputed, most before treatment principles were fully defined in 1980. Fourteen of these 16 patients (88%) had type III lesions. Refracture occurred in 22 patients, most as the result of significant trauma, in the absence of external brace support. Twelve of the 19 refractures, retreated with PEMFs and casts, healed on this regime. Episodic use of PEMFs proved effective in controlling stress fractures in several patients until they reached puberty. PEMFs, which are associated with no known risk, appear to be an effective, conservative adjunct in the management of this therapeutically challenging, congenital lesions.
自1973年以来,91例先天性胫骨假关节患者接受了脉冲电磁场(PEMFs)治疗,除4例患者外,其余患者均随访至青春期。病变根据X线表现进行分层。I型和II型病变的间隙宽度小于5mm。III型病变为萎缩性、纺锤形,间隙超过5mm。I型和II型病变的总体成功率为60例中的43例(72%)。在尝试手术修复之前就诊的28例患者中,8例I型病变中有7例愈合(88%),而20例II型病变中有16例仅通过PEMFs和固定就愈合了(80%)。只有19%(31例中的6例)的III型病变愈合,其中只有1例不需要手术。91条肢体中有16条(18%)最终被截肢,大多数是在1980年治疗原则完全确定之前。这16例患者中有14例(88%)患有III型病变。22例患者发生了再骨折,大多数是在没有外部支具支撑的情况下因严重创伤导致的。19例再骨折患者中有12例接受了PEMFs和石膏治疗,在此治疗方案下愈合。间歇性使用PEMFs被证明在控制几名患者的应力性骨折方面有效,直到他们进入青春期。PEMFs没有已知风险,似乎是治疗这种具有挑战性的先天性病变的一种有效的保守辅助手段。