Laonigro Irma, Correale Michele, Di Biase Matteo, Altomare Emanuele
Department of Medical and Occupational Sciences, Institute of Internal Medicine, University of Foggia, Foggia, Italy.
Eur J Heart Fail. 2009 May;11(5):453-62. doi: 10.1093/eurjhf/hfp037. Epub 2009 Mar 30.
Alcoholic patients who consume >90 g of alcohol a day for >5 years are at risk of developing asymptomatic alcoholic cardiomyopathy (ACM). Those patients who continue to drink may become symptomatic and develop signs and symptoms of heart failure (HF). This distinct form of congestive HF is responsible for 21-36% of all cases of non-ischaemic dilated cardiomyopathy in Western Society. Without complete abstinence, the 4 year mortality for ACM is close to 50%. This short review summarizes the experimental and clinical evidence regarding the role of alcohol in the pathophysiology of ACM and HF.
每天饮酒超过90克且持续5年以上的酒精性患者有患无症状酒精性心肌病（ACM）的风险。那些继续饮酒的患者可能会出现症状，并发展为心力衰竭（HF）的体征和症状。这种独特形式的充血性心力衰竭在西方社会所有非缺血性扩张型心肌病病例中占21% - 36%。如果不完全戒酒，ACM患者的4年死亡率接近50%。这篇简短的综述总结了关于酒精在ACM和HF病理生理学中作用的实验和临床证据。
