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使用埃克塞特柄进行股骨嵌压植骨术——瑞典的经验:对1989年至2002年间进行的1305例翻修手术的生存率分析。

Femoral impaction bone grafting with the Exeter stem - the Swedish experience: survivorship analysis of 1305 revisions performed between 1989 and 2002.

作者信息

Ornstein E, Linder L, Ranstam J, Lewold S, Eisler T, Torper M

机构信息

Department of Orthopaedic Surgery, Hässleholm Hospital, SE-28125, Hässleholm, Sweden.

出版信息

J Bone Joint Surg Br. 2009 Apr;91(4):441-6. doi: 10.1302/0301-620X.91B4.21319.

Abstract

We identified 1305 femoral impaction bone grafting revisions using the Exeter stem performed between 1989 and 2002 in 30 hospitals throughout Sweden. There were 1188 patients with a mean age of 71 years (29 to 94) followed up for between five and 18 years. The participating departments reported 70 further revisions in total, of which 57 could also be identified on the Swedish National Arthroplasty Registry. Kaplan-Meier survivorship for all causes of failure was 94.0% (95% confidence interval (CI) 92 to 96) for women and 94.7% (95% CI, 92 to 96) for men at 15 years. Survivorship at 15 years for aseptic loosening was 99.1% (95% CI 98.4 to 99.5), for infection 98.6% (95% CI 97.6 to 99.2), for subsidence 99.0% (95% CI 98.2 to 99.4) and for fracture 98.7% (95% CI 97.9 to 99.2) Statistically significant predictors of failure were the year in which revision was conducted (p < 0.001). The number of previous revisions was slightly above the level of significance (p = 0.056). Age, gender, the length of the stem and previous septic loosening were not predictors of failure (p = 0.213, p = 0.399, p = 0.337, p = 0.687, respectively). The difference in survivorship between high- and low-volume departments was only 3% at ten years. We conclude that impaction bone grafting with the Exeter stem has an excellent long-term survivorship following revision arthroplasty. The technique of impaction grafting appears to be reliable, can be learned rapidly and produces a predictably low incidence of aseptic loosening.

摘要

我们在瑞典全国30家医院中,确定了1989年至2002年间采用埃克塞特柄进行的1305例股骨嵌压植骨翻修手术。共有1188例患者,平均年龄71岁(29至94岁),随访时间为5至18年。参与研究的科室总共报告了另外70例翻修手术,其中57例也可在瑞典国家关节成形术登记处查到。15年时,所有失败原因导致的Kaplan-Meier生存率,女性为94.0%(95%置信区间[CI]92至96),男性为94.7%(95%CI,92至96)。无菌性松动导致的15年生存率为99.1%(95%CI 98.4至99.5),感染为98.6%(95%CI 97.6至99.2),下沉为99.0%(95%CI 98.2至99.4),骨折为98.7%(95%CI 97.9至99.2)。具有统计学意义的失败预测因素是进行翻修手术的年份(p<0.001)。既往翻修手术次数略高于显著性水平(p = 0.056)。年龄、性别、柄的长度和既往无菌性松动不是失败的预测因素(分别为p = 0.213、p = 0.399、p = 0.337、p = 0.687)。高手术量科室和低手术量科室在10年时的生存率差异仅为3%。我们得出结论,采用埃克塞特柄进行嵌压植骨在翻修关节成形术后具有出色的长期生存率。嵌压植骨技术似乎可靠,可快速掌握,且无菌性松动发生率低且可预测。

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