Handa Shinya, Tomiha Sadanori, Kose Katsumi, Haishi Tomoyuki
Institute of Applied Physics, University of Tsukuba, Tsukuba, Ibaraki, Japan.
Magn Reson Med Sci. 2009;8(1):39-42. doi: 10.2463/mrms.8.39.
We repeatedly measured the trabecular bone (TB) microstructure of the distal radius in 5 healthy volunteers using a compact magnetic resonance (MR) imaging system to evaluate the reproducibility of the TB structural parameters. The compact system was specially developed with a 1.0-tesla permanent magnet for the distal radius in a previous study. We measured the distal radius using a 3-dimensional (3D), driven-equilibrium, spin-echo sequence (repetition time/echo time=80 ms/10 ms, number of excitations=1, field of view=76.8 mm x 57.6 mm x 16.0 mm, acquisition time=17 min, matrix size=512 x 384 x 32, voxel size=150 microm x 150 microm x 500 microm) and analyzed the acquired image datasets using the virtual bone biopsy system developed by the University of Pennsylvania. Root mean squares of the coefficients of variance expressed as percentages ranged from 2.9% to 14% for the TB structural parameters. Therefore, we concluded that this compact MR imaging system could be used to assess TB microstructure of the distal radius and provide results consistent with those using a whole-body MR imaging system and showing the promise of this system for evaluating bone quality in clinical settings.
我们使用紧凑型磁共振（MR）成像系统，对5名健康志愿者的桡骨远端小梁骨（TB）微观结构进行了反复测量，以评估TB结构参数的可重复性。在之前的一项研究中，该紧凑型系统是专门为桡骨远端配备1.0特斯拉永磁体而开发的。我们使用三维（3D）驱动平衡自旋回波序列（重复时间/回波时间 = 80毫秒/10毫秒，激励次数 = 1，视野 = 76.8毫米×57.6毫米×16.0毫米，采集时间 = 17分钟，矩阵大小 = 512×384×32，体素大小 = 150微米×150微米×500微米）对桡骨远端进行测量，并使用宾夕法尼亚大学开发的虚拟骨活检系统分析采集到的图像数据集。TB结构参数的变异系数百分比的均方根范围为2.9%至14%。因此，我们得出结论，这种紧凑型MR成像系统可用于评估桡骨远端的TB微观结构，并提供与使用全身MR成像系统一致的结果，显示出该系统在临床环境中评估骨质量的前景。
