Roadcap David W, Bear James E
Nat Cell Biol. 2009 Apr;11(4):375-6. doi: 10.1038/ncb0409-375.
The assembly of actin networks is dependent on nucleation-promoting factors. A new study identifies JMY as a protein containing two separate nucleation-promoting activities that shuttles between the nucleus and the cytoplasm and promotes cell migration. These observations indicate that JMY is an important factor controlling actin dynamics in motile cells.
肌动蛋白网络的组装依赖于成核促进因子。一项新研究确定JMY是一种含有两种独立成核促进活性的蛋白质，它在细胞核和细胞质之间穿梭并促进细胞迁移。这些观察结果表明，JMY是控制运动细胞中肌动蛋白动力学的重要因子。
