神经肌肉疾病中心脏受累的管理：综述
Management of cardiac involvement in neuromuscular diseases: review.
作者信息
Bouhouch Rachida, Elhouari Tarik, Oukerraj Latifa, Fellat Ibtissam, Zarzur Jamila, Bennani Rajaa, Arharbi Mhamed
机构信息
Service de Cardiologie B, CHU Ibn Sina Rabat, MAROC.
出版信息
Open Cardiovasc Med J. 2008;2:93-6. doi: 10.2174/1874192400802010093. Epub 2008 Oct 22.
Abstract
Neuromuscular Diseases are a heterogeneous molecular, clinical and prognosis group. Progress has been achieved in the understanding and classification of these diseases.Cardiac involvement in neuromuscular diseases namely conduction disorders, ventricular dilatation and dilated cardiomyopathy with its impact on prognosis, is often dissociated from the peripheral myopathy. Therefore, close surveillance is mandatory in the affected patients. In this context, preventive therapy (beta-blockers and angiotensin converting enzyme inhibitors) has been recently recommended in the most common Neuromuscular Diseases, Duchenne Muscular Dystrophy and Myotonic Dystrophy.
摘要
神经肌肉疾病是一组分子、临床和预后各不相同的疾病。在这些疾病的认识和分类方面已经取得了进展。神经肌肉疾病中的心脏受累，即传导障碍、心室扩张和扩张型心肌病及其对预后的影响，通常与周围肌病无关。因此，对受影响的患者进行密切监测是必不可少的。在这种情况下，最近建议在最常见的神经肌肉疾病——杜兴氏肌营养不良症和强直性肌营养不良症中采用预防性治疗（β受体阻滞剂和血管紧张素转换酶抑制剂）。
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