骨形态发生蛋白6调控铁代谢。
BMP6 orchestrates iron metabolism.
作者信息
Camaschella Clara
机构信息
Università Vita-Salute & Istituto Scientifico San Raffaele, Division of Genetics and Cell Biology, Milano, Italy.
出版信息
Nat Genet. 2009 Apr;41(4):386-8. doi: 10.1038/ng0409-386.
PMID:19338078
Abstract
The small liver peptide hepcidin is a major regulator of systemic iron homeostasis in mammals, adapting iron absorption to the body's demands. Two new studies now identify BMP6 as the key endogenous regulator of hepcidin.
摘要
小肝脏肽铁调素是哺乳动物全身铁稳态的主要调节因子，使铁吸收适应身体需求。两项新研究现已确定骨形态发生蛋白6（BMP6）是铁调素的关键内源性调节因子。
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