Danilov A B, Frolov A A, Fadeev A V, Korzhavina V B
Zh Vyssh Nerv Deiat Im I P Pavlova. 2009 Jan-Feb;59(1):107-15.
Electrode for selective nociception specific stimulation was described by H. Kaube et al. in 2000. The aim of this work was to test this electrode in assessment of nociceptive reactions of the segmental and suprasegmental levels. The method of nociception specific blink reflex based on the use of this electrode was applied in a modified variant for examination of patients with a tension type headache. A decrease in the nociceptive reflex threshold was revealed in patients with episodic headaches (as compared to healthy volunteers). Both the reflex and pain thresholds were decreased in patients with a chronic headache. These results indicate the sensitization of nociceptive structures in patients with a headache. Cerebral evoked potentials elicited by skin stimulation of face and extremities with Kaube electrode were studied in healthy volunteers. The dominance of the late components (100-300 ms) considered to be of nociceptive origin was revealed in the pattern of evoked potentials. Thus, the electrode assures a high degree of selectivity of the pain-specific stimulation. Its adaptation for assessment of various nociceptive reactions can perfect the neurophysiological methods of nociception studies.
H. 考贝等人在2000年描述了用于选择性伤害性感受特异性刺激的电极。这项工作的目的是在评估节段性和节段上水平的伤害性反应中测试该电极。基于使用该电极的伤害性感受特异性眨眼反射方法以改良变体应用于紧张型头痛患者的检查。发作性头痛患者(与健康志愿者相比)显示出伤害性反射阈值降低。慢性头痛患者的反射阈值和疼痛阈值均降低。这些结果表明头痛患者伤害性结构的致敏。在健康志愿者中研究了用考贝电极刺激面部和四肢皮肤所诱发的脑诱发电位。在诱发电位模式中发现被认为起源于伤害性感受的晚期成分(100 - 300毫秒)占主导。因此,该电极确保了疼痛特异性刺激的高度选择性。其用于评估各种伤害性反应的适应性可以完善伤害性感受研究的神经生理学方法。