心理唤醒过程中疼痛与伤害性眨眼反射之间的分离。
Dissociation between pain and the nociceptive blink reflex during psychological arousal.
作者信息
Koh Chee Wan, Drummond Peter D
机构信息
School of Psychology, Murdoch University, South Street, Murdoch, Perth, WA 6150, Australia.
出版信息
Clin Neurophysiol. 2006 Apr;117(4):851-4. doi: 10.1016/j.clinph.2005.12.004. Epub 2006 Feb 2.
OBJECTIVE
To investigate the effect of psychological arousal on pain ratings and the R2 component of the electrically evoked blink reflex to a 'pure' noiciceptive stimulus.
METHODS
Pain ratings and R2 to a noiciceptive stimulus (pulse width 0.3ms, 2mA, delivered from a concentric electrode attached to the supraorbital region of the forehead) were investigated in 16 healthy participants before and during a serial subtraction task, and in 16 control participants who sat quietly during nociceptive stimulation.
RESULTS
Pain ratings decreased whereas R2 amplitude increased during the serial subtraction task.
CONCLUSIONS
Supra-spinal rather than spinal mechanisms inhibited pain perception during psychological arousal. Moreover, psychological arousal facilitated the R2 component of the blink reflex to a nociception-specific stimulus.
SIGNIFICANCE
Supra-spinal influences need to be considered during clinical evaluation of the trigeminal nociceptive blink reflex.
目的
研究心理唤醒对疼痛评分以及电诱发眨眼反射的R2成分（针对“纯”伤害性刺激）的影响。
方法
对16名健康参与者在进行连续减法任务前和任务过程中，以及16名在伤害性刺激期间安静坐着的对照参与者，研究其对伤害性刺激（脉冲宽度0.3毫秒，2毫安，通过连接在前额眶上区域的同心电极施加）的疼痛评分和R2。
结果
在连续减法任务期间，疼痛评分降低，而R2波幅增加。
结论
在心理唤醒期间，脊髓以上而非脊髓机制抑制了疼痛感知。此外，心理唤醒促进了眨眼反射的R2成分对伤害性特异性刺激的反应。
意义
在三叉神经伤害性眨眼反射的临床评估中，需要考虑脊髓以上的影响。
Zotero 插件