Vardi Yoram, Levine Laurence A, Chen Juza, Hatzimouratidis Konstantinos, Sohn Michael
Rambam Medical Center & Technion Faculty of Medicine, Haifa Israel.
Department of Urology, Rush University Medical Center, Chicago, IL, USA.
J Sex Med. 2009 Apr;6(4):903-909. doi: 10.1111/j.1743-6109.2009.01214.x.
Peyronie's disease (PD) is a relatively common disorder affecting middle aged men. Conservative nonsurgical treatments include oral, topical, and intra-lesional pharmacotherapies, vacuum stretching, and mechanical traction.
Four people with expertise and/or interest in the area of PD were asked to contribute their opinions with regard to the safety and efficacy of nonsurgical conservative treatments.
To provide food for thought, discussion, and possible further research in a poorly discussed area of sexual medicine.
Of the four experts writing on the topic, one believes a combination of medical therapy and penile traction has positive potential for curvature. Another feels that although medical therapies have potential to alleviate pain, there is little evidence to show that they help with curvature or that penile traction helps. A third expert proposes dividing the disease into phases, where patients in the acute phase may benefit from conservative therapy, whereas patients whose disease is stable require surgical intervention. The last expert agrees that the therapy should depend on the stage of the disease, but believes like the first expert that there is a role for traction therapy for patients with stable disease.
There is a need for guidelines for nonsurgical therapies for patients with PD, but there is a paucity of evidence as to their efficacy.
佩罗尼氏病（PD）是一种影响中年男性的相对常见病症。保守的非手术治疗方法包括口服、局部和病灶内药物治疗、真空牵引和机械牵引。
邀请了四位在佩罗尼氏病领域有专业知识和/或兴趣的人就非手术保守治疗的安全性和有效性发表意见。
为性医学中一个讨论较少的领域提供思考、讨论和可能进一步研究的素材。
在撰写该主题的四位专家中，一位认为药物治疗和阴茎牵引相结合对改善弯曲有积极潜力。另一位认为，尽管药物治疗有缓解疼痛的潜力，但几乎没有证据表明它们有助于改善弯曲或阴茎牵引有帮助。第三位专家建议将该病分为不同阶段，急性期患者可能从保守治疗中受益，而病情稳定的患者则需要手术干预。最后一位专家同意治疗应取决于疾病阶段，但与第一位专家一样，认为对于病情稳定的患者，牵引治疗有作用。
需要为佩罗尼氏病患者的非手术治疗制定指南，但关于其疗效的证据很少。
