Hauptmann A, Diemer T, Weidner W
Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen, Rudolf-Buchheim-Str. 7, 35390 Giessen, Deutschland.
Urologe A. 2011 May;50(5):609-20. doi: 10.1007/s00120-011-2517-7.
Peyronie's disease is a benign disorder of the penis but the etiology is still unknown. A wound healing disorder after repetitive microtraumatic lesions with inelastic scar formation of the tunica albuginea potentially leads to the typical symptoms of penile plaque formation, penile pain, deviation and erectile dysfunction. A non-surgical therapy based on a clear pathophysiology does not exist although the benefit of several conservative treatment options is under discussion. In the stable stage of the disease patients with Peyronie's disease frequently undergo penile surgery. Depending on the deviation angle, the penile length and the erectile dysfunction different straightening surgery can be performed. This article provides an overview of the natural history of the disease and describes present conservative management strategies and common surgical techniques for penile straightening.
佩罗尼氏病是一种阴茎的良性疾病，但其病因仍不清楚。重复性微创伤性损伤后伤口愈合障碍，白膜形成无弹性瘢痕，可能导致阴茎斑块形成、阴茎疼痛、弯曲和勃起功能障碍等典型症状。尽管几种保守治疗方案的益处仍在讨论中，但基于明确病理生理学的非手术治疗方法并不存在。在疾病的稳定期，佩罗尼氏病患者常接受阴茎手术。根据弯曲角度、阴茎长度和勃起功能障碍情况，可以进行不同的矫正手术。本文概述了该疾病的自然病程，并描述了目前阴茎矫正的保守治疗策略和常见手术技术。
