Avery Rachel, Startup Mike, Calabria Karen
School of Psychology, University of Newcastle, Callaghan, NSW 2308, Australia.
Psychiatry Res. 2009 May 15;167(1-2):36-46. doi: 10.1016/j.psychres.2008.04.016. Epub 2009 Mar 31.
The aim of the present study was to assess the role of psychological factors, specifically effort, coping, and negative expectancy appraisals, in addition to executive functioning and depression, in accounting for negative symptoms broadly defined. Fifty inpatients with acute schizophrenia participated in a study with a cross-sectional design. All of the psychological variables had significant partial correlations with some of the measures of negative symptoms when depression was controlled. A series of multiple regression analyses indicated that executive functioning only made a significant unique contribution to the prediction of affective flattening, whereas psychological factors made unique contributions to the variance in each of the negative symptom subscales apart from affective flattening, as well as to the negative symptom total score, accounting for 9% to 19% of the variance. These results suggest that, in addition to neuropsychological variables, psychological variables are important for understanding negative symptoms in acute schizophrenia.
本研究的目的是评估心理因素,特别是努力、应对和消极预期评估,以及执行功能和抑郁,在广义上解释阴性症状方面所起的作用。五十名急性精神分裂症住院患者参与了一项横断面设计的研究。当控制抑郁时,所有心理变量与一些阴性症状测量指标均存在显著的部分相关性。一系列多元回归分析表明,执行功能仅对情感平淡的预测有显著的独特贡献,而心理因素对除情感平淡外的每个阴性症状子量表的方差以及阴性症状总分有独特贡献,解释了9%至19%的方差。这些结果表明,除神经心理学变量外,心理变量对于理解急性精神分裂症的阴性症状也很重要。