Katz S, Katzka I, Platt N, Hajdu E O, Bassett E
Am J Dig Dis. 1977 Apr;22(4):355-64. doi: 10.1007/BF01072194.
Saline colonic lavage in 74 patients with chronic ulcerative colitis was performed utilizing a commercially available dental irrigating unit through a polyethylene catheter in the biopsy channel of a colonoscope or through a sigmoidoscope via a lavage-aspirating double-lumen probe. Six patients were found with colonic carcinoma. Two diagnoses of malignancy were established by cytologic smears and cell block alone. Two patients had positive mucosal biopsies and cell block. One patient with a hepatic flexure carcinoma and a second patient with a malignancy proximal to the left colon stricture were missed by these techniques. Considering the established proclivity for carcinoma in these patients, it is felt that segmental lavage in areas of stricutre, grossly dostorted mucosa, or endoscopically inaccessible areas represents a valuable adjunct in the diagnosis of carcinoma in chronic ulcerative colitis.
对74例慢性溃疡性结肠炎患者进行生理盐水结肠灌洗，通过市售牙科冲洗装置，经结肠镜活检通道中的聚乙烯导管，或经乙状结肠镜通过灌洗-抽吸双腔探头进行。发现6例结肠癌患者。仅通过细胞学涂片和细胞块确立了2例恶性肿瘤诊断。2例患者黏膜活检和细胞块呈阳性。这些技术漏诊了1例肝曲癌患者和另1例左半结肠狭窄近端恶性肿瘤患者。考虑到这些患者已确定的患癌倾向，认为在狭窄、黏膜严重变形或内镜无法到达的区域进行分段灌洗是慢性溃疡性结肠炎癌诊断中的一项有价值的辅助手段。
