Evans D J, Pollock D J
Gut. 1972 Jul;13(7):566-70. doi: 10.1136/gut.13.7.566.
Four cases are described in which ulcerative colitis was complicated by carcinoma and in which the extent of the accompanying in-situ carcinoma (precancer) was determined. The extent of the in-situ carcinoma was very variable and in all cases the rectum was spared in whole or part. Search for in-situ carcinoma in rectal biopsies will fail to indicate the development of malignancy in some patients with ulcerative colitis. Alternative methods of cancer detection in this group are discussed.
本文描述了4例溃疡性结肠炎并发癌的病例，并确定了其伴随的原位癌（癌前病变）范围。原位癌的范围差异很大，所有病例中直肠全部或部分未受累。在直肠活检中寻找原位癌，无法提示某些溃疡性结肠炎患者发生恶性肿瘤的情况。本文还讨论了该组患者癌症检测的替代方法。
