Jang Sung Ho, Park Kyung-A, Ahn Sang Ho, Cho Yoon Woo, Byun Woo Mok, Son Su Min, Choi Jin Ho, Kwon Young Hyun
Department of Physical Medicine and Rehabilitation, Yeungnam University College of Medicine, Daegu, Republic of Korea.
NeuroRehabilitation. 2009;24(2):159-64. doi: 10.3233/NRE-2009-0464.
Diffusion tensor image tractography (DTT) can visualize white matter tracts and provide a powerful vehicle with which to investigate the neural pathway at the subcortical level. We attempted to demonstrate the clinical significance of transcallosal fibers (TCF) originating from the corticospinal tract in patients with corona radiata infarct located below the corpus callosum, using diffusion tensor image tractography (DTT). Forty patients with corona radiata infarct located below the corpus callosum and 26 control subjects were enrolled in this study. We classified the DTT findings as follows: no transcallosal fiber from the CST (type A), transcallosal fiber ended in the corpus callosum or connected to the cortex of the opposite hemisphere (type B), and transcallosal fiber that descended toward the lesion after passing through the corpus callosum (type C). Type C indicated that the presence of transcallosal fibers starting from the CST of the unaffected hemisphere was significantly more prevalent in the patients, and these patients showed the poorest motor function. It seems that transcallosal fibers originated from the CST of the unaffected hemisphere, and fibers descending toward the lesion in patients with corona radiata infarct may act to compensate for motor deficits.
扩散张量成像纤维束示踪技术（DTT）能够可视化白质纤维束，并为研究皮质下水平的神经通路提供了一种强大的手段。我们试图通过扩散张量成像纤维束示踪技术（DTT）来证明胼胝体下方辐射冠梗死患者中源自皮质脊髓束的胼胝体纤维（TCF）的临床意义。本研究纳入了40例胼胝体下方辐射冠梗死患者和26例对照受试者。我们将DTT结果分类如下：无来自皮质脊髓束的胼胝体纤维（A型）、胼胝体纤维止于胼胝体或连接至对侧半球皮质（B型），以及胼胝体纤维穿过胼胝体后向病变处下行（C型）。C型表明，在患者中，源自未受影响半球皮质脊髓束的胼胝体纤维的存在明显更为普遍，且这些患者的运动功能最差。似乎源自未受影响半球皮质脊髓束的胼胝体纤维，以及在辐射冠梗死患者中向病变处下行的纤维可能起到补偿运动缺陷的作用。
