Departments of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
Eur J Gastroenterol Hepatol. 2009 Sep;21(9):1092-4. doi: 10.1097/MEG.0b013e328328f47f.
We here report a case of celiac disease and Budd Chiari syndrome. This 19-year-old boy was diagnosed to have portal hypertension in another hospital when he had developed variceal bleeding. In our hospital, he was found to have occlusion of all three hepatic veins as the cause of portal hypertension. On a routine endoscopy, he was found to have scalloping of duodenal folds. Suspecting celiac disease, he was investigated further. He did have positive serology for celiac disease as well as suggestive histology. He was found to be deficient for protein C and protein S. He was managed conservatively and put on gluten-free diet, with which he showed clinical improvement. A review of literature showed that only 14 previous cases of this combination were recorded and except for one all were from North Africa or southern Europe.
我们在此报告一例乳糜泻和布加综合征。这名 19 岁男孩曾因静脉曲张出血在另一家医院被诊断为门静脉高压症。在我院，他被发现三肝静脉全部闭塞是导致门静脉高压的原因。在常规内镜检查中，他发现十二指肠褶皱呈扇贝状。考虑乳糜泻，进一步检查。他的乳糜泻血清学检查呈阳性，组织学检查也有提示意义。他还存在蛋白 C 和蛋白 S 缺乏。他接受了保守治疗，并采用无麸质饮食，症状得到了改善。文献复习显示，此前仅有 14 例此类联合病例记录，除 1 例外均来自北非或南欧。
