Hu Y
Department of Epidemiology, Tianjin Medical College.
Zhonghua Liu Xing Bing Xue Za Zhi. 1991 Aug;12(4):197-9.
A pair matched case-control study was conducted in 301 pairs female patients with essential hypertension and their controls. The data was analysed by the multiple conditional Logistic regression. The results showed the risk factors associated with hypertension were: body weight (OR = 1.17, 95% CI: 1.12-1.23), the family history of hypertension (OR = 2.18, 95% CI: 1.49-3.21) the family income (OR = 0.73, 95% CI: 0.56-0.94), heart rate (OR = 2.30, 95% CI: 1.41-3.76). OR for the age of menarche was significantly different before and after being adjusted by body weight. There were no relationship between the age of menopause, the age of the first birth, parties, oral contraceptive use or smoking status and hypertension. The paper suggested that the difference of prevalence of hypertension in male and female over 45 years old cannot be explained by menopause or the factors on birth in women.
对301对女性原发性高血压患者及其对照进行了配对病例对照研究。采用多条件Logistic回归分析数据。结果显示,与高血压相关的危险因素有:体重(比值比=1.17,95%置信区间:1.12-1.23)、高血压家族史(比值比=2.18,95%置信区间:1.49-3.21)、家庭收入(比值比=0.73,95%置信区间:0.56-0.94)、心率(比值比=2.30,95%置信区间:1.41-3.76)。初潮年龄的比值比在经体重调整前后有显著差异。绝经年龄、初产年龄、生育次数、口服避孕药使用情况或吸烟状况与高血压之间均无关联。该论文表明,45岁以上男性和女性高血压患病率的差异不能用女性的绝经或生育因素来解释。