Chen W, Wu X, Zhang Y
Zhongshan Medical University, Guangzhou.
Zhonghua Liu Xing Bing Xue Za Zhi. 1994 Feb;15(1):23-6.
Basing on the prevalence survey, 94 cases were diagnosed as simple senile systolic hypertension and 67 cases as non simple senile systolic hypertension, and 136 persons with normal blood pressure were sampled as control. Two case-control studies were conducted, then the etiologic factors of two types of hypertension were compared. Among age, sex, smoking, drinking, mental incidence, family history of hypertension, body height, body weight, body weight index, blood sugar, TC, TG, HDL-c, etc., a total of 18 factors, mono variate unconditional logistic regression analysis showed that the occurrence of ISH associated with age, family history of hypertension, mental incidence and blood sugar, and that the risk factors of NISH were body weight index, body weight, smoking, drinking, mental incidence, and TC. Further multi-unconditional logistic regression turned out that mental incidence, family history of hypertension and blood sugar entered the model of ISH, and that the body weight index, smoking, mental incidence, blood and TC entered the model of ISH. The study showed that the etiologic factors of ISH differed from those of NISH, which was a syndrome differed from NISH.
基于患病率调查，94例被诊断为单纯老年收缩期高血压，67例为非单纯老年收缩期高血压，并抽取136例血压正常者作为对照。进行了两项病例对照研究，然后比较了两种类型高血压的病因因素。在年龄、性别、吸烟、饮酒、精神因素、高血压家族史、身高、体重、体重指数、血糖、总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-c）等共18个因素中，单变量无条件逻辑回归分析显示，单纯收缩期高血压的发生与年龄、高血压家族史、精神因素和血糖有关，而非单纯收缩期高血压的危险因素为体重指数、体重、吸烟、饮酒、精神因素和总胆固醇。进一步的多无条件逻辑回归结果显示，精神因素、高血压家族史和血糖进入了单纯收缩期高血压模型，而体重指数、吸烟、精神因素、血脂和总胆固醇进入了非单纯收缩期高血压模型。研究表明，单纯收缩期高血压的病因因素与非单纯收缩期高血压不同，它是一种与非单纯收缩期高血压不同的综合征。
