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[使用温德-犹他量表西班牙语版对安蒂奥基亚家庭成年人的注意缺陷多动行为表型维度进行研究]

[Attention deficit hyperactivity behavioral phenotype dimensions of adults from Antioquian families using the Wender-Utah Scale -Spanish version].

作者信息

Trujillo-Orrego N, Pineda D A, Arango C P, Puerta I C, Lopera F, Aguirre-Acevedo D C, Hincapie-Henao L, Pineda-Alvarez D E, Arcos-Burgos M, Muenke M

机构信息

Universidad de Antioquia, Medellín, Colombia.

出版信息

Rev Neurol. 2009;48(8):400-6.

Abstract

INTRODUCTION

The Wender-Utah Rating Scale (WURS) has been used for retrospective screening of attention deficit hyperactivity disorders (ADHD) symptoms and its comorbidities.

AIM

To establish the ADHD behavioral phenotype dimensions of adults from 140 Antioquian families with genetic segregation for ADHD diagnosis, using the WURS -Spanish version.

SUBJECTS AND METHODS

392 adults from both genders, belonging to nuclear and multigenerational families with one or more ADHD affected members were selected. The Composite International Diagnostic Interview (CIDI) for mental disorder was administered to establish the gold standard diagnosis of ADHD through the long life. All participants fulfill the WURS. Exploratory and confirmatory factor analyses were done to determine the behavioral dimensions of the ADHD phenotype.

RESULTS

A factor structure of four dimensions was derived, measuring behavioral decontrol, hyperactivity, inattention and anxiety, and which explained the 60% of the total variance.

CONCLUSIONS

The behavioral adult ADHD phenotype in the Antioquian families was conformed by four dimensions, which could be used in heritability and linkage future studies.

摘要

引言

温德-犹他评定量表(WURS)已被用于回顾性筛查注意力缺陷多动障碍(ADHD)症状及其共病情况。

目的

使用WURS西班牙语版,确定来自140个患有ADHD的安蒂奥基亚家庭的成年人的ADHD行为表型维度,这些家庭存在ADHD的遗传分离现象。

研究对象与方法

选取了392名来自核心家庭和多代家庭的成年男女,这些家庭中有一名或多名成员患有ADHD。采用复合国际诊断访谈(CIDI)进行精神障碍诊断,以确定ADHD的终生金标准诊断。所有参与者均完成了WURS测试。进行探索性和验证性因素分析,以确定ADHD表型的行为维度。

结果

得出了一个四维因素结构,测量行为失控、多动、注意力不集中和焦虑,这解释了总方差的60%。

结论

安蒂奥基亚家庭中成人ADHD的行为表型由四个维度构成,可用于未来的遗传度和连锁研究。

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