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中风幸存者对镜像视觉反馈的功能连接调制：一项脑磁图研究。

Modulation of Functional Connectivity in Response to Mirror Visual Feedback in Stroke Survivors: An MEG Study.

作者信息

Tai Ruei-Yi, Zhu Jun-Ding, Chen Chih-Chi, Hsieh Yu-Wei, Cheng Chia-Hsiung

机构信息

Department of Neurology, Taipei Medical University Hospital, Taipei 110, Taiwan.

Taipei Neuroscience Institute, Taipei Medical University, Taipei 110, Taiwan.

出版信息

Brain Sci. 2021 Sep 28;11(10):1284. doi: 10.3390/brainsci11101284.

DOI:10.3390/brainsci11101284
PMID:34679347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8533793/
Abstract

BACKGROUND

Several brain regions are activated in response to mirror visual feedback (MVF). However, less is known about how these brain areas and their connectivity are modulated in stroke patients. This study aimed to explore the effects of MVF on brain functional connectivity in stroke patients.

MATERIALS AND METHODS

We enrolled 15 stroke patients who executed Bilateral-No mirror, Bilateral-Mirror, and Unilateral-Mirror conditions. The coherence values among five brain regions of interest in four different frequency bands were calculated from magnetoencephalographic signals. We examined the differences in functional connectivity of each two brain areas between the Bilateral-No mirror and Bilateral-Mirror conditions and between the Bilateral-Mirror and Unilateral-Mirror conditions.

RESULTS

The functional connectivity analyses revealed significantly stronger connectivity between the posterior cingulate cortex and primary motor cortex in the beta band (adjusted = 0.04) and possibly stronger connectivity between the precuneus and primary visual cortex in the theta band (adjusted = 0.08) in the Bilateral-Mirror condition than those in the Bilateral-No mirror condition. However, the comparisons between the Bilateral-Mirror and Unilateral-Mirror conditions revealed no significant differences in cortical coherence in all frequency bands.

CONCLUSIONS

Providing MVF to stroke patients may modulate the lesioned primary motor cortex through visuospatial and attentional cortical networks.

摘要

背景

多个脑区会对镜像视觉反馈（MVF）产生反应而被激活。然而，对于这些脑区及其连接性在中风患者中是如何被调节的，我们了解得较少。本研究旨在探讨MVF对中风患者脑功能连接性的影响。

材料与方法

我们招募了15名中风患者，他们执行双侧无镜像、双侧镜像和单侧镜像条件。从脑磁图信号中计算出四个不同频段的五个感兴趣脑区之间的相干值。我们检查了双侧无镜像和双侧镜像条件之间以及双侧镜像和单侧镜像条件之间每两个脑区功能连接性的差异。

结果

功能连接性分析显示，与双侧无镜像条件相比，在双侧镜像条件下，β频段后扣带回皮层与初级运动皮层之间的连接性显著更强（校正P = 0.04），θ频段楔前叶与初级视觉皮层之间的连接性可能更强（校正P = 0.08）。然而，双侧镜像和单侧镜像条件之间的比较显示，所有频段的皮层相干性均无显著差异。

结论

为中风患者提供MVF可能通过视觉空间和注意力皮层网络调节受损的初级运动皮层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/524968de9014/brainsci-11-01284-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/65d46e54e251/brainsci-11-01284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/0f2ffb31d729/brainsci-11-01284-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/c63f7545113a/brainsci-11-01284-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/524968de9014/brainsci-11-01284-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/65d46e54e251/brainsci-11-01284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/0f2ffb31d729/brainsci-11-01284-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/c63f7545113a/brainsci-11-01284-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/942b/8533793/524968de9014/brainsci-11-01284-g004.jpg

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2
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Clin Neurophysiol. 2020 Oct;131(10):2333-2340. doi: 10.1016/j.clinph.2020.06.030. Epub 2020 Jul 22.
3
Mirror Therapy in Stroke Rehabilitation: Current Perspectives.
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Ther Clin Risk Manag. 2020 Feb 7;16:75-85. doi: 10.2147/TCRM.S206883. eCollection 2020.
4
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5
Modulation of Motor Cortical Activities by Action Observation and Execution in Patients with Stroke: An MEG Study.脑卒患者通过动作观察和执行对运动皮质活动的调节：一项 MEG 研究。
Neural Plast. 2019 Oct 30;2019:8481371. doi: 10.1155/2019/8481371. eCollection 2019.
6
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7
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8
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9
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