Babb Brian R, Loushine Robert J, Bryan Thomas E, Ames Jason M, Causey Mark S, Kim Jongryul, Kim Young Kyung, Weller R Norman, Pashley David H, Tay Franklin R
Department of Endodontics, School of Dentistry, Medical College of Georgia, Augusta, GA 30912-1129, USA.
J Endod. 2009 Apr;35(4):578-82. doi: 10.1016/j.joen.2009.01.005.
The latest generation of methacrylate resin-based sealers has eliminated the use of separate self-etching primers by incorporating acidic resin monomers in the sealers to render them self-adhesive to dentin. This study examined the adhesive strengths, interfacial ultrastructure, and tracer penetration of a nonetching (EndoREZ; Ultradent, South Jordan, UT) and two self-adhesive methacrylate resin-based sealers (MetaSEAL; Parkell, Farmington, NY, and RealSeal SE; SybronEndo, Orange, CA) when they were applied to radicular dentin following the manufacturers' recommended use of EDTA as the active final rinse. A modified push-out testing design was used to evaluate the dislodgement of core-free sealers. The mixed sealers were placed in dimensionally identical, artificially created canal spaces prepared in the coronal, middle, and apical thirds of radicular dentin. After setting, each sealer-filled cavity was subjected to compressive loading until failure. Additional specimens were prepared for transmission electron microscopy to examine the ultrastructure and nanoleakage within the sealer-radicular dentin interface. The two self-adhesive sealers MetaSEAL and RealSeal SE exhibited higher push-out strengths than the nonetching sealer EndoREZ when EDTA was used as the active final rinse. All three sealers showed a 1- to 1.5-microm thick zone of partially demineralized dentin, with the EDTA dentin demineralization effect masking the true self-etching potential of MetaSEAL and RealSeal SE. The true self-etching potential of self-adhesive sealers is a clinically important attribute that should be further investigated. Incomplete smear layer removal from the apical third of instrumented canal walls may jeopardize the performance of self-adhesive sealers should they fail to self-etch without the adjunctive use of calcium chelating irrigants.
最新一代的甲基丙烯酸酯树脂类封闭剂通过在封闭剂中加入酸性树脂单体，使其对牙本质具有自粘性，从而不再使用单独的自酸蚀底漆。本研究检测了一种非酸蚀封闭剂（EndoREZ；Ultradent，南乔丹，犹他州）以及两种自粘性甲基丙烯酸酯树脂类封闭剂（MetaSEAL；Parkell，法明顿，纽约州，和RealSeal SE；SybronEndo，奥兰治，加利福尼亚州）在按照制造商推荐使用乙二胺四乙酸（EDTA）作为活性终末冲洗剂应用于根管牙本质时的粘结强度、界面超微结构和示踪剂渗透情况。采用改良的推出试验设计来评估无核封闭剂的脱位情况。将混合后的封闭剂置于在根管牙本质冠部、中部和根尖三分之一处制备的尺寸相同的人工根管空间中。固化后，对每个充满封闭剂的窝洞施加压缩载荷直至破坏。制备额外的标本用于透射电子显微镜检查，以观察封闭剂与根管牙本质界面的超微结构和纳米渗漏情况。当使用EDTA作为活性终末冲洗剂时，两种自粘性封闭剂MetaSEAL和RealSeal SE的推出强度高于非酸蚀封闭剂EndoREZ。所有三种封闭剂均显示出1至1.5微米厚的部分脱矿牙本质区域，EDTA对牙本质的脱矿作用掩盖了MetaSEAL和RealSeal SE真正的自酸蚀潜力。自粘性封闭剂真正的自酸蚀潜力是一个临床上重要的特性，应进一步研究。如果在未辅助使用钙螯合剂冲洗液的情况下自粘性封闭剂不能自酸蚀，那么从预备根管壁根尖三分之一处未完全去除的玷污层可能会影响其性能。
