van Leeuwen Marieke, van den Berg Stéphanie M, Peper Jiska S, Hulshoff Pol Hilleke E, Boomsma Dorret I
Department of Biological Psychology, VU University, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands.
Behav Genet. 2009 May;39(3):245-54. doi: 10.1007/s10519-009-9264-1. Epub 2009 Apr 4.
This study investigates the genetic relationship among reading performance, IQ, verbal and visuospatial working memory (WM) and short-term memory (STM) in a sample of 112, 9-year-old twin pairs and their older siblings. The relationship between reading performance and the other traits was explained by a common genetic factor for reading performance, IQ, WM and STM and a genetic factor that only influenced reading performance and verbal memory. Genetic variation explained 83% of the variation in reading performance; most of this genetic variance was explained by variation in IQ and memory performance. We hypothesize, based on these results, that children with reading problems possibly can be divided into three groups: (1) children low in IQ and with reading problems; (2) children with average IQ but a STM deficit and with reading problems; (3) children with low IQ and STM deficits; this group may experience more reading problems than the other two.
本研究调查了112对9岁双胞胎及其年长同胞样本中阅读能力、智商、言语和视觉空间工作记忆(WM)以及短期记忆(STM)之间的遗传关系。阅读能力与其他特质之间的关系可由阅读能力、智商、工作记忆和短期记忆的共同遗传因素以及仅影响阅读能力和言语记忆的遗传因素来解释。遗传变异解释了阅读能力变异的83%;大部分这种遗传方差可由智商和记忆表现的变异来解释。基于这些结果,我们推测,有阅读问题的儿童可能可分为三组:(1)智商低且有阅读问题的儿童;(2)智商平均但短期记忆有缺陷且有阅读问题的儿童;(3)智商低且短期记忆有缺陷的儿童;该组可能比其他两组经历更多的阅读问题。