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[一项关于儿童和青少年智力与处理速度遗传率的双胞胎研究]

[A twin study on intelligence and processing speed heritability of children and adolescent].

作者信息

Zhang Xiao-wei, Huang Yi, Xiang Yun, Gao Xin, Situ Ming-jing, Fang Hui, Zhang Yi, Fu Yi-xiao, Jia Lu, Meng Hua-qing, Ma Xiao-hong, Wang Ying-cheng, Liu Xie-he, Li Tao

机构信息

Mental Health Center, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041 PR China.

出版信息

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2009 Jun;26(3):326-30. doi: 10.3760/cma.j.issn.1003-9406.2009.03.020.

Abstract

OBJECTIVE

To explore the effects of the genetic and environmental factors on intelligence of children and adolescent from the Southwest China Prospective Twin Registry (SCPT).

METHODS

The intelligence was investigated by using the Wechsler Intelligence Scale for Children (C-WISC) in 333 twin pairs aged 6-16 years. The effects of genetic and environmental factors on IQ were analyzed by using structural equation modeling (SEM) and correlation analysis method. The effects in different sex and age groups in this population were also investigated.

RESULTS

Genetic influence accounted for 0.43 of total IQ variance and 0.37 of verbal IQ in 6-16 years old children and adolescent, but there was no significant genetic effect on performance IQ. The heritability of children aged 10-16 years was higher than that of those aged 6-10 years (total IQ: 0.82 vs 0.00, verbal IQ: 0.80 vs 0.00, performance IQ:0.51 vs 0.00). In males the heritability of verbal IQ (0.47) was higher than that in females (0.05). The shared environmental influences accounted fo r the majority of variance of performance IQ in both males and females.

CONCLUSION

There is moderate heritability on the total IQ and verbal IQ, while shared environmental factors played important roles on the variance of performance IQ. The heritability of IQ, verbal IQ and performance IQ are higher in older children and adolescent than that in younger children.

摘要

目的

利用中国西南地区双生子前瞻性队列(SCPT),探讨遗传和环境因素对儿童及青少年智力的影响。

方法

采用韦氏儿童智力量表(C-WISC)对333对6至16岁的双胞胎进行智力测试。运用结构方程模型(SEM)和相关分析方法分析遗传和环境因素对智商的影响。同时研究了该人群中不同性别和年龄组的影响情况。

结果

在6至16岁儿童及青少年中,遗传影响占总智商方差的0.43,占言语智商方差的0.37,但对操作智商无显著遗传效应。10至16岁儿童的遗传度高于6至10岁儿童(总智商:0.82对0.00,言语智商:0.80对0.00,操作智商:0.51对0.00)。男性言语智商的遗传度(0.47)高于女性(0.05)。共同环境影响在男性和女性的操作智商方差中占大部分。

结论

总智商和言语智商存在中等程度的遗传度,而共同环境因素在操作智商方差中起重要作用。年龄较大的儿童及青少年在智商、言语智商和操作智商方面的遗传度高于年龄较小的儿童。

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