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戈谢病中骨髓炎的诊断。两例观察报告。

Diagnosing osteomyelitis in Gaucher's disease. Observations on two cases.

作者信息

Sziklas J J, Negrin J A, Rosshirt W, Rosenberg R J, Spencer R P

机构信息

Department of Radiology, Hartford Hospital, Connecticut 06115.

出版信息

Clin Nucl Med. 1991 Jul;16(7):487-9. doi: 10.1097/00003072-199107000-00004.

DOI:10.1097/00003072-199107000-00004
PMID:1934792
Abstract

Bone scans in two patients with Gaucher's disease were reported as consistent with Gaucher's-associated osseous crises. A bone-radiogallium subtraction study was also initially negative in each individual (although it later became positive in one). At surgery both patients were seen to have osteomyelitis. These two cases point out the difficulty in attempting to diagnose osteomyelitis in the presence of Gaucher's bone disease. A possible role for MRI in such instances was mentioned. Also noted was clinical reluctance to accept a diagnosis of osteomyelitis (positive bone-radiogallium subtraction study) in an afebrile Gaucher's patient.

摘要

两名戈谢病患者的骨扫描报告显示与戈谢病相关的骨危象相符。骨放射性镓减影研究最初在每个个体中也均为阴性(尽管其中一人后来转为阳性)。手术时发现两名患者均患有骨髓炎。这两个病例指出了在存在戈谢骨病的情况下诊断骨髓炎的困难。文中提到了MRI在这种情况下可能发挥的作用。还指出临床上不愿意接受一名无发热的戈谢病患者被诊断为骨髓炎(骨放射性镓减影研究阳性)。

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Diagnosing osteomyelitis in Gaucher's disease. Observations on two cases.戈谢病中骨髓炎的诊断。两例观察报告。
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引用本文的文献

1
Scintigraphic findings on 99mTc-MDP, 99mTc-sestamibi and 99mTc-HMPAO images in Gaucher's disease.戈谢病患者99mTc-MDP、99mTc-司他米比和99mTc-HMPAO图像的闪烁扫描结果。
Eur J Nucl Med. 1996 Apr;23(4):466-70. doi: 10.1007/BF01247378.