Bilchik T R, Heyman S
Department of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia.
Clin Nucl Med. 1992 Apr;17(4):279-82. doi: 10.1097/00003072-199204000-00003.
Two patients with known type 1 Gaucher's disease had signs and symptoms of osteomyelitis. Decreased perfusion and impaired uptake were seen on bone scan. Patient 1 had a culture-negative aspirate of the site. Patient 2 had no surgical procedures. Both improved on bed rest and nonsteroidal anti-inflammatory agents. It is difficult to distinguish osteomyelitis clinically from pseudo-osteomyelitis. The authors suggest that photopenia on bone scan performed within 1 to 3 days of presentation is suggestive of pseudo-osteomyelitis in Gaucher's disease.
两名已知患有1型戈谢病的患者出现了骨髓炎的体征和症状。骨扫描显示灌注减少和摄取受损。患者1该部位的抽吸物培养结果为阴性。患者2未进行外科手术。两人经卧床休息和使用非甾体抗炎药后病情均有改善。临床上很难将骨髓炎与假性骨髓炎区分开来。作者认为，在出现症状后1至3天内进行的骨扫描中出现光减少提示戈谢病患者存在假性骨髓炎。
