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利用双能X线吸收法评估杜氏肌营养不良症患者的局部身体成分:局部去脂体重与定量肌力的相关性

Assessment of regional body composition with dual-energy X-ray absorptiometry in Duchenne muscular dystrophy: correlation of regional lean mass and quantitative strength.

作者信息

Skalsky Andrew J, Han Jay J, Abresch Richard T, Shin Chris S, McDonald Craig M

机构信息

Department of Physical Medicine and Rehabilitation, University of California, Davis, 4860 Y Street, Suite 3850, Sacramento, California 95817, USA.

出版信息

Muscle Nerve. 2009 May;39(5):647-51. doi: 10.1002/mus.21212.

DOI:10.1002/mus.21212
PMID:19347922
Abstract

The purpose of this study was to assess regional body composition and its correlation with regional strength in Duchenne muscular dystrophy (DMD) subjects and able-bodied controls. Regional dual-energy X-ray absorptiometry (DEXA) measurements and isometric strength were obtained for 23 DMD subjects and 23 control subjects. DMD subjects showed a decreased regional lean mass (P < 0.001). The correlation between regional strength and regional lean mass was stronger for controls than for DMD subjects. DMD subjects had decreased regional lean mass, increased regional fat mass, and decreased strength. Muscle Nerve 39: 647-651, 2009.

摘要

本研究的目的是评估杜氏肌营养不良症(DMD)患者和健全对照者的局部身体成分及其与局部力量的相关性。对23名DMD患者和23名对照者进行了局部双能X线吸收法(DEXA)测量和等长肌力测试。DMD患者的局部瘦体重降低(P < 0.001)。对照者局部力量与局部瘦体重之间的相关性强于DMD患者。DMD患者的局部瘦体重降低、局部脂肪量增加且力量下降。《肌肉与神经》39: 647 - 651, 2009年。

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