Sieg K G, Harty J R, Simmons M, Preston D F, Erickson H M
Department of Psychiatry, University of Kansas Medical Center, Kansas City.
Clin Nucl Med. 1991 Sep;16(9):665-7. doi: 10.1097/00003072-199109000-00011.
Tc-99m HMPAO was used to evaluate cerebral perfusion in a patient with tuberous sclerosis. The SPECT images demonstrated reduced HMPAO uptake in regions corresponding with MRI-confirmed locations of cortical tubers. These results indicate that the lesions are characterized by vascular perfusion deficits and support the hypothesis that cortical tubers result from developmental abnormalities of the embryonic central nervous system.
锝-99m六甲基丙二胺肟（Tc-99m HMPAO）用于评估一名结节性硬化症患者的脑灌注情况。单光子发射计算机断层扫描（SPECT）图像显示，与磁共振成像（MRI）证实的皮质结节位置相对应的区域，Tc-99m HMPAO摄取减少。这些结果表明，这些病变的特征是血管灌注不足，并支持了皮质结节是由胚胎中枢神经系统发育异常所致的假说。
