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导管消融治疗瘢痕相关性室性心动过速。

Catheter ablation for scar-related ventricular tachycardias.

作者信息

Raymond Jean-Marc, Sacher Frederic, Winslow Robert, Tedrow Usha, Stevenson William G

出版信息

Curr Probl Cardiol. 2009 May;34(5):225-70. doi: 10.1016/j.cpcardiol.2009.01.002.

Abstract

Patients with scar-related ventricular tachycardia (VT) are subject to frequent arrhythmia recurrences; antiarrhythmic drug therapy has been disappointing due to poor efficacy and side effects. Patients receiving multiple implantable cardioverter-defibrillator shocks because of VT have impaired quality of life. The role of catheter ablation in the treatment of ventricular arrhythmias has been increasing in the last 2 decades. As more knowledge is gained about the mechanisms of VT, the potential for doing ablation has increased. Now, multiple VTs and unstable VTs can be targeted by ablation strategies. Also, electroanatomic mapping systems have made substrate mapping feasible. The purpose of this article is to review the selection and preparation of patients who require catheter ablation for scar-related VT, the different mapping techniques, and the ablation strategies employed. An overview of the pathophysiology of scar-related VT and the variety of heart diseases that are related to scar-related VT is provided.

摘要

患有瘢痕相关室性心动过速(VT)的患者心律失常频繁复发;抗心律失常药物治疗由于疗效不佳和副作用而令人失望。因室性心动过速接受多次植入式心脏复律除颤器电击的患者生活质量受损。在过去20年中,导管消融在室性心律失常治疗中的作用不断增加。随着对室性心动过速机制的了解越来越多,进行消融的可能性也增加了。现在,多种室性心动过速和不稳定室性心动过速都可以通过消融策略进行靶向治疗。此外,电解剖标测系统使基质标测成为可能。本文的目的是回顾需要导管消融治疗瘢痕相关室性心动过速的患者的选择和准备、不同的标测技术以及所采用的消融策略。本文还概述了瘢痕相关室性心动过速的病理生理学以及与瘢痕相关室性心动过速相关的各种心脏病。

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