Hodzic Amra, Kaas Amanda, Muckli Lars, Stirn Aglaja, Singer Wolf
Department of Neurophysiology, Max Planck Institute for Brain Research, Deutschordenstr. 46, D-60528 Frankfurt am Main, Germany.
Neuroimage. 2009 May 1;45(4):1264-71. doi: 10.1016/j.neuroimage.2009.01.027. Epub 2009 Feb 6.
In the human brain information about bodies and faces is processed in specialized cortical regions named EBA and FBA (extrastriate and fusiform body area) and OFA and FFA (occipital and fusiform face area), respectively. Here we investigate with functional magnetic resonance imaging (fMRI) the cortical areas responsible for the identification of individual bodies and the distinction between 'self' and 'others'. To this end we presented subjects with images of unfamiliar and familiar bodies and their own body. We identified separate coactivation networks for body-detection (processing body related information), body-identification (processing of information relating to individual bodies) and self-identification (distinction of self from others). Body detection involves the EBA in both hemispheres, and in the right hemisphere: the FBA and areas in the IPL (inferior parietal lobe). Body identification involves areas in the inferior frontal gyrus (IFG) of both hemispheres and in the right hemisphere areas in the medial frontal gyrus (MFG), in the cingulate gyrus (CG), in the central (CS) and the post-central sulcus (PCS), in the inferior parietal lobe (IPL) and the FBA. When the recognition of one's own body is contrasted to the identification of familiar bodies, differential activation is observed in areas of the inferior parietal lobe (IPL) and inferior parietal sulcus (IPS) of the right hemisphere, and in the posterior orbital gyrus (pOrbG) and in the lateral occipital gyrus (LOG) of the left hemisphere. Thus, identification of individual bodies and self-other distinction involve in addition to the classical occipito-parietal network a parieto-frontal network. Interestingly, the EBA shows no differential activation for distinctions between familiar or unfamiliar bodies or recognition of one's own body.
在人类大脑中，有关身体和面部的信息分别在名为EBA和FBA（纹外和梭状身体区）以及OFA和FFA（枕叶和梭状面部区）的专门皮质区域进行处理。在这里，我们使用功能磁共振成像（fMRI）研究负责识别个体身体以及区分“自我”和“他人”的皮质区域。为此，我们向受试者展示了陌生和熟悉的身体以及他们自己身体的图像。我们确定了用于身体检测（处理与身体相关的信息）、身体识别（处理与个体身体相关的信息）和自我识别（区分自我与他人）的单独的共同激活网络。身体检测涉及双侧半球的EBA，以及右侧半球的FBA和顶下小叶（IPL）中的区域。身体识别涉及双侧半球额下回（IFG）中的区域以及右侧半球额内侧回（MFG）、扣带回（CG）、中央沟（CS）和中央后沟（PCS）、顶下小叶（IPL）和FBA中的区域。当将对自己身体的识别与对熟悉身体的识别进行对比时，在右侧半球的顶下小叶（IPL）和顶下沟（IPS）区域以及左侧半球的眶后回（pOrbG）和枕外侧回（LOG）中观察到差异激活。因此，除了经典的枕顶网络外，个体身体的识别和自我与他人的区分还涉及一个顶额网络。有趣的是，EBA在熟悉或陌生身体之间的区分或对自己身体的识别方面没有显示出差异激活。
