人类主要组织相容性复合体的免疫遗传学
Immunogenetics of the human major histocompatibility complex.
作者信息
Duquesnoy R J
机构信息
University of Pittsburgh School of Medicine, Pennsylvania.
出版信息
Clin Lab Med. 1991 Sep;11(3):509-36.
PMID:1934962
Abstract
The biologic significance of the human major histocompatibility complex (MHC), also referred to as HLA, is well known through its influence on transplant immunity and its association with many diseases. This article attempts to summarize recent progress in the field of HLA polymorphisms. Topics discussed include the genetic basis of HLA, methods to determine HLA polymorphisms, and definitions of HLA Class I and II polymorphisms.
摘要
人类主要组织相容性复合体（MHC），也称为HLA，其生物学意义通过对移植免疫的影响以及与许多疾病的关联而广为人知。本文试图总结HLA多态性领域的最新进展。讨论的主题包括HLA的遗传基础、确定HLA多态性的方法以及HLA I类和II类多态性的定义。
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