Suppr超能文献

[血培养在成人细菌性肺炎球菌肺炎抗生素治疗中的应用价值]

[Utility of blood cultures on antibiotic therapy in adult bacteremic pneumococcal pneumonia].

作者信息

Mathurin L Sebastián, Agüero L Andrés, Jaimet A Celia, Schälibaum G Erica, Demergasso S Mariela, Acuña S Victoria

机构信息

Servicio de Clínica Médica, Hospital Intendente Carrasco, Rosario, Argentina.

出版信息

Rev Chilena Infectol. 2009 Feb;26(1):9-17. Epub 2009 Mar 23.

Abstract

We evaluated the utility of blood cultures in the therapeutic management of patients with bacteremic pneumococcal pneumonia admitted to an internal medicine unit, in a retrospective observational study. Forty-nine patients were included, 75.5% were men, mean age 51.1 years. All S. pneumoniae strains were susceptible to penicillin. Four patients died. In 15.5% the treatment was modified narrowing antibiotic spectrum, in 51% cases it was changed to bencylpenicillin or amoxicillin exclusively, but only in 16% within the first 4 days. In 12 cases the prescription coincided with the oral switch therapy to amoxicillin. Due to the benefits and potential advantages of penicillin in diminishing the incidence of antibiotic resistance and reducing costs, it is important to work on prescription habits among physicians. This is especially important in the case of penicillin and the opportune moment of therapy change, improving the use of the microbiological report.

摘要

在一项回顾性观察研究中,我们评估了血培养在入住内科病房的菌血症性肺炎链球菌肺炎患者治疗管理中的作用。纳入了49例患者,75.5%为男性,平均年龄51.1岁。所有肺炎链球菌菌株均对青霉素敏感。4例患者死亡。15.5%的患者治疗方案调整为缩小抗生素谱,51%的病例仅改为使用苄青霉素或阿莫西林,但仅16%在最初4天内进行了调整。12例患者的处方与改为口服阿莫西林的转换治疗一致。鉴于青霉素在降低抗生素耐药性发生率和降低成本方面的益处和潜在优势,改善医生的处方习惯很重要。在青霉素及治疗方案适时调整的情况下尤其重要,要更好地利用微生物学报告。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验