F-18氟代脱氧葡萄糖正电子发射断层显像-计算机断层扫描成像在复发性脑胶质肉瘤中的应用

F-18 FDG PET-CT imaging in recurrent cerebral gliosarcoma.

作者信息

Ho Linh Thuy, Wassef Heidi, Henderson Robert, Seto John

机构信息

Department of Radiology, Division of Nuclear Medicine, PET Imaging Science Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA.

出版信息

Clin Nucl Med. 2009 Mar;34(3):153-4. doi: 10.1097/RLU.0b013e3181966fc6.

DOI:10.1097/RLU.0b013e3181966fc6

PMID:19352277

Abstract

We report the F-18 FDG PET-CT appearance of recurrent gliosarcoma (GS) with extracranial extension in a 47-year-old man who underwent surgical resection of a right frontal GS 5 months earlier. F-18 FDG PET demonstrated moderate uptake in the recurrent disease. GS is a very rare, biphasic primary neoplasm of the central nervous system, composed of glioblastoma multiforme mixed with a sarcomatous component. It occurs in adults of middle age and carries a poor prognosis. The median survival reported is less than a year. The results suggest that F-18 FDG PET imaging may be useful in detecting recurrent GS.

摘要

我们报告了一名47岁男性复发性胶质肉瘤（GS）伴颅外扩展的F-18 FDG PET-CT表现，该患者5个月前接受了右额叶GS的手术切除。F-18 FDG PET显示复发性病变有中度摄取。GS是一种非常罕见的中枢神经系统双相原发性肿瘤，由多形性胶质母细胞瘤与肉瘤成分混合组成。它发生于中年成年人，预后较差。报告的中位生存期不到一年。结果表明，F-18 FDG PET成像可能有助于检测复发性GS。