From the Department of Nuclear Medicine, University Hospital, LMU Munich, Munich.
German Cancer Consortium (DKTK), partner site Munich.
Clin Nucl Med. 2019 Nov;44(11):923-924. doi: 10.1097/RLU.0000000000002790.
A 51-year-old man presented with recurrent gliosarcoma and increasing cough over the last months. On F-FDG PET/CT, solid lung masses with high F-FDG uptake were present. A biopsy taken from a lung lesion indicated distant metastases from gliosarcoma. Gliosarcoma, a rare malignant central nervous system tumor, presents with extracranial metastases in only less than 10%. As highlighted by this case, F-FDG PET/CT can be used for whole-body staging in patients with metastatic brain tumor. Vice versa, highly F-FDG-avid lung lesions in patients with brain tumors should lead to distant metastases as differential diagnosis despite their rare occurrence.
一位 51 岁男性因复发性胶质肉瘤和过去几个月持续咳嗽而就诊。在 F-FDG PET/CT 上，可见肺部有实性肿块，FDG 摄取较高。从肺部病变处取的活检提示胶质肉瘤发生了远处转移。胶质肉瘤是一种罕见的恶性中枢神经系统肿瘤，不到 10%的患者会出现颅外转移。正如本病例所强调的那样，FDG PET/CT 可用于有脑转移瘤的患者进行全身分期。相反，尽管脑肿瘤患者肺部 FDG 摄取高的病变很少见，但应将其作为鉴别诊断，提示存在远处转移。
