Division of Dermatology, Department of Medicine, King Saud Bin Abdulaziz University, King Fahad National Guard Hospital, King Abdulaziz Medical City, P.O. Box 22490, Riyadh 11426, Kingdom of Saudi Arabia.
Eur J Pediatr. 2010 Jan;169(1):117-9. doi: 10.1007/s00431-009-0981-5. Epub 2009 Apr 8.
Kwashiorkor is one of the severe forms of protein-energy malnutrition. Many characteristic dermatoses can be seen in children suffering from kwashiorkor, and some are pathognomonic. Here, we report an infant who presented with diarrhea and skin signs of kwashiorkor, and duodenal biopsy was consistent with Crohn's disease. The patient was treated with prednisolone administered orally in a tapering course plus azathioprine, in addition to nutritional supplementation. The general condition of the patient quickly improved and his skin lesions completely resolved within 2 weeks. Kwashiorkor is a serious potentially fatal disease that occurs less often in developed countries leading to low index of suspicion by physicians and pediatricians in those regions. Occasionally, dermatologists have the rare chance of alerting pediatricians to the diagnosis of kwashiorkor, thus making a difference in the care of this disease.
夸希奥科病是一种严重的蛋白质能量营养不良症。患有夸希奥科病的儿童会出现许多特征性的皮肤病,其中一些具有特征性。在这里,我们报告了一例以腹泻和夸希奥科病皮肤征象就诊的婴儿,十二指肠活检符合克罗恩病。该患者接受了泼尼松龙口服递减疗程加硫唑嘌呤治疗,同时进行营养补充。患者的一般情况迅速改善,皮肤病变在 2 周内完全消退。夸希奥科病是一种严重的潜在致命疾病,在发达国家较少见,导致这些地区的医生和儿科医生的怀疑指数较低。偶尔,皮肤科医生有机会提醒儿科医生注意夸希奥科病的诊断,从而在治疗这种疾病方面有所不同。