Chen C Z, Wang Y S, Feng Z R, Ye C X, Zhu H S, Jiang B Y
Department of Cardiothoracic Surgery, Renji Hospital, Shanghai Second Medical University.
Chin Med J (Engl). 1991 Sep;104(9):747-52.
To prolong the time of heart preservation, we modified the Wicomb's perfusion apparatus, in which oxygen flow acts as the source of power and provides oxygenation for the perfused myocardium. Ten adult porcine hearts which had been preserved for 24 hours were resuscitated successfully and continued to beat steadily for more than 1.5-3 hours after reperfusion. Myocardial ultrastructure was observed at the end of preservation and 15-120 minutes after reperfusion. The damages of the myocardial ultrastructure at the end of preservation were reversible.
为延长心脏保存时间，我们对Wicomb灌注装置进行了改良，该装置以氧流作为动力源并为灌注的心肌提供氧合作用。10个经24小时保存的成年猪心脏成功复苏，并在再灌注后稳定跳动超过1.5至3小时。在保存结束时以及再灌注后15至120分钟观察心肌超微结构。保存结束时心肌超微结构的损伤是可逆的。
