Feng G G
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou.
Zhonghua Yan Ke Za Zhi. 1991 Jul;27(4):227-30.
44 cases (56 eyes of 29 males and 15 females) of lymphocytic inflammatory pseudotumor were analysed. The average age of onset was 40.6 years. The chief manifestations consisted of orbital mass, proptosis, edema of the eyelids and bulbar conjunctiva, and limited eyeball motility. ESR was accelerated in 11 of 13 patients tested. Seral antibody of EB virus was positive in 2 of 3 patients examined. Immunohistochemically, all 3 patients examined showed polyclonality. A diffuse lymphocytic infiltration with other inflammatory cells and fibrovascular proliferation was the basic pathological picture. Histopathologically, the disease was classified into the diffuse infiltrative, fibrotic, and mixed types. The pathogenesis, the significance of immunohistochemical examinations, and treatment were discussed.
对44例淋巴细胞性炎性假瘤患者（29例男性、15例女性，共56只眼）进行了分析。平均发病年龄为40.6岁。主要表现包括眼眶肿块、眼球突出、眼睑及球结膜水肿，以及眼球活动受限。13例接受检测的患者中有11例血沉加快。3例接受检查的患者中有2例EB病毒血清抗体呈阳性。免疫组化检查显示，所有3例接受检查的患者均呈多克隆性。基本病理表现为弥漫性淋巴细胞浸润伴其他炎性细胞及纤维血管增生。组织病理学上，该病分为弥漫浸润型、纤维化型和混合型。对其发病机制、免疫组化检查的意义及治疗进行了讨论。
