Zhang M D, Huang S R
Department of Ophthalmology, Worker's General Hospital, Benxi Steel Co.
Zhonghua Yan Ke Za Zhi. 1991 Jul;27(4):231-4.
The levels of circulating immune complexes (CIC) in 77 patients with endogenous uveitis (EU) were found significantly higher than in healthy controls, and also closely correlated with activity of the disease. The CIC level declined during remission and became essentially normal when the disease recovered. CIC was positive in 20 (37.7%) of the 77 cases, and the positive rate was the highest (58.6%) in patients with acute EU. Retinal soluble antigen was found in CIC of 9 patients. The serum C3 level was in negative correlation with the CIC level, and restored to normal on recovery of the disease. The findings indicated that CIC played an important role in the pathogenesis of EU.
77例内因性葡萄膜炎（EU）患者的循环免疫复合物（CIC）水平显著高于健康对照组，且与疾病活动度密切相关。病情缓解期CIC水平下降，疾病恢复时基本恢复正常。77例患者中20例（37.7%）CIC呈阳性，急性EU患者的阳性率最高（58.6%）。9例患者的CIC中发现视网膜可溶性抗原。血清C3水平与CIC水平呈负相关，疾病恢复时恢复正常。这些发现表明CIC在EU的发病机制中起重要作用。
