Radda T M, Menzel E J, Gnad H D
Klin Monbl Augenheilkd. 1983 Sep;183(3):211-2. doi: 10.1055/s-2008-1054906.
The serum of 63 patients suffering from various clinical types of endogenous uveitis with unknown etiology was investigated for the presence of circulating immune complexes (CIC). None of the patients was suffering from a systemic disease usually associated with CIC. Significantly elevated CIC levels were detected in 2 women with chronic cyclitis. One of them was also suffering from paresis of the facial nerve. The investigation reported here indicates that C1q-binding CIC are of no importance in the pathogenesis of endogenous uveitis. On the one hand one should consider the possibility of local IC formation, on the other hand one should be aware of the fact that IC does not always represent a pathogenic factor but that it may also occur as a secondary phenomenon after non-immunologic tissue destruction.
对63例患有各种临床类型的病因不明的内源性葡萄膜炎患者的血清进行了循环免疫复合物(CIC)检测。所有患者均未患有通常与CIC相关的全身性疾病。在2例慢性睫状体炎女性患者中检测到CIC水平显著升高。其中1例还患有面神经麻痹。此处报告的研究表明,C1q结合型CIC在内源性葡萄膜炎的发病机制中并不重要。一方面应考虑局部IC形成的可能性,另一方面应意识到IC并不总是代表致病因素,它也可能作为非免疫性组织破坏后的继发现象出现。