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霍乱疫情——苏丹南部,2007年

Cholera outbreak--southern Sudan, 2007.

出版信息

MMWR Morb Mortal Wkly Rep. 2009 Apr 10;58(13):337-41.

Abstract

Vibrio cholerae causes cholera, an acute infectious diarrheal disease that can result in death without appropriate therapy, depending on the severity of the disease. War, poverty, inadequate sanitation, and large numbers of refugees and internally displaced persons (IDPs) are major precursors to cholera outbreaks. In 2005, Southern Sudan ended its 22-year civil war with North Sudan; as a result, IDPs and refugees are returning to the south. During April--June 2007, investigators from the Southern Sudan Field Epidemiology and Laboratory Training Program (SS-FELTP) and CDC investigated a cholera outbreak in the town of Juba, Southern Sudan. This report summarizes the results of that investigation, which found that 3,157 persons were diagnosed with suspected cholera during January--June 2007, with 74 deaths resulting from the disease. An environmental investigation revealed suboptimal hygiene practices and a lack of water and sanitation infrastructure in Juba. A case-control study indicated that persons less likely to have cholera were more likely to have consumed hot meals containing meat during the outbreak. Contaminated food or water were not identified as possible sources of the cholera outbreak in Juba. However, this might be attributed to limitations of the study, including small sample size. Cholera can reach epidemic proportions if adequate control measures are not implemented early. Mass media campaigns are important for current and new residents in Juba to understand the importance of proper food handling, clean water, and optimal hygiene practices to prevent the spread of cholera.

摘要

霍乱弧菌可引发霍乱,这是一种急性感染性腹泻疾病,若未进行恰当治疗,根据疾病严重程度可能会导致死亡。战争、贫困、卫生条件差以及大量难民和境内流离失所者是霍乱暴发的主要先兆。2005年,苏丹南部结束了与苏丹北部长达22年的内战;因此,境内流离失所者和难民正返回南部。2007年4月至6月期间,苏丹南部现场流行病学和实验室培训项目(SS - FELTP)及美国疾病控制与预防中心(CDC)的调查人员对苏丹南部朱巴镇的一次霍乱暴发进行了调查。本报告总结了该调查结果,结果发现,在2007年1月至6月期间,有3157人被诊断为疑似霍乱,其中74人因病死亡。一项环境调查显示,朱巴镇存在卫生习惯欠佳以及缺乏水和卫生基础设施的情况。一项病例对照研究表明,在霍乱暴发期间,较少可能感染霍乱的人更有可能食用了含肉的热餐。在朱巴,受污染的食物或水未被确定为霍乱暴发的可能源头。然而,这可能归因于该研究的局限性,包括样本量小。如果不及早实施充分的控制措施,霍乱可能会达到流行程度。大众媒体宣传活动对于朱巴的现有居民和新居民了解正确的食品处理、清洁用水和良好卫生习惯对预防霍乱传播的重要性至关重要。

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