Departamento de Biología de Organismos, Universidad Simón Bolivar, Caracas, Venezuela.
Int J Environ Health Res. 2009 Aug;19(4):279-89. doi: 10.1080/09603120802460368.
The aim of this study was to characterize the virulence properties and the antimicrobial resistance of Vibrio cholerae isolates from a coastal area of the Caribbean Sea. Three V. cholerae isolates were obtained from seawater and plankton using the HP selective medium for Helicobacter pylori. These V. cholerae isolates belonged to the non-O1, non-O139 serogroups and they did not have cholera toxin genes. They were resistant to penicillins and some cephalosporins and were sensitive to netilmicin, tetracyclines, sulfamethoxazole-trimethoprim and quinolones. This is the first study that provides biochemical and molecular evidence of non-O1, non-O139 V. cholerae isolates, non-toxigenic, carrying antibiotic resistance in seawater and plankton from a coastal area of the Caribbean Sea.
本研究旨在描述加勒比海沿海地区分离的霍乱弧菌的毒力特性和抗菌药物耐药性。使用幽门螺杆菌选择性培养基从海水和浮游生物中获得了 3 株霍乱弧菌。这些霍乱弧菌属于非 O1、非 O139 血清群,且不携带霍乱毒素基因。它们对青霉素和一些头孢菌素类药物耐药,但对奈替米星、四环素类、磺胺甲噁唑-甲氧苄啶和喹诺酮类药物敏感。这是首次在加勒比海沿海地区的海水和浮游生物中发现非 O1、非 O139、非产毒、携带抗生素耐药性的霍乱弧菌的生化和分子证据。