HIV感染者常规疫苗接种的最佳时机。

Optimal timing of routine vaccination in HIV-infected persons.

作者信息

Crane Heidi M, Dhanireddy Shireesha, Kim H Nina, Ramers Christian, Dellit Timothy H, Kitahata Mari M, Harrington Robert D

机构信息

Center for AIDS and STD Research, University of Washington, Harborview Medical Center, Box 359931, 325 9th Avenue, Seattle, WA 98104, USA.

出版信息

Curr HIV/AIDS Rep. 2009 May;6(2):93-9. doi: 10.1007/s11904-009-0014-z.

DOI:10.1007/s11904-009-0014-z

PMID:19358780

Abstract

Vaccine recommendations for those with HIV require continual updating as additional research becomes available. Timing of vaccinations among HIV-infected individuals is a key area of uncertainty. This is particularly true for those who may soon initiate highly active antiretroviral therapy (HAART) because immune reconstitution due to HAART often improves responses to vaccines. However, risks of delaying vaccination include that the patient may be exposed to the pathogen or lost to follow-up before vaccination. We review recent studies on the timing of routine vaccination of HIV-infected individuals.

摘要

随着更多研究成果的出现，针对艾滋病毒感染者的疫苗接种建议需要不断更新。艾滋病毒感染者的疫苗接种时间是一个关键的不确定领域。对于那些可能很快开始接受高效抗逆转录病毒疗法（HAART）的人来说尤其如此，因为HAART引起的免疫重建通常会改善对疫苗的反应。然而，延迟接种疫苗的风险包括患者可能在接种疫苗前接触病原体或失访。我们综述了近期关于艾滋病毒感染者常规疫苗接种时间的研究。