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垂体外肢端肥大症

Extrapituitary acromegaly.

作者信息

Melmed S

机构信息

Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California.

出版信息

Endocrinol Metab Clin North Am. 1991 Sep;20(3):507-18.

PMID:1935918
Abstract

Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to their management is provided.

摘要

肢端肥大症可能由下丘脑肽、生长激素释放激素（GHRH）或生长激素（GH）本身的异位分泌引起。下丘脑肿瘤、类癌和胰腺肿瘤占这些病例的大多数。本文讨论了由这些非垂体肿瘤引起的肢端肥大症的发病机制、病因和诊断，并提供了其治疗方法。

相似文献

1
Extrapituitary acromegaly.垂体外肢端肥大症
Endocrinol Metab Clin North Am. 1991 Sep;20(3):507-18.
2
Ectopic acromegaly.异位性肢端肥大症
Endocrinol Metab Clin North Am. 1992 Sep;21(3):575-95.
3
Neuroendocrine tumors secreting growth hormone-releasing hormone: Pathophysiological and clinical aspects.分泌生长激素释放激素的神经内分泌肿瘤：病理生理与临床方面
Pituitary. 2006;9(3):221-9. doi: 10.1007/s11102-006-0267-0.
4
[Ectopic GHRH (growth hormone-releasing hormone) producing tumor].[产生异位生长激素释放激素（GHRH）的肿瘤]
Nihon Rinsho. 2006 Sep 28;Suppl 3:279-82.
5
Acromegaly caused by ectopic growth hormone: a rare manifestation of a bronchial carcinoid.异位生长激素引起的肢端肥大症：支气管类癌的一种罕见表现。
Ann Thorac Surg. 2008 Jan;85(1):330-2. doi: 10.1016/j.athoracsur.2007.06.072.
6
Ectopic secretion of growth hormone-releasing hormone (GHRH) in neuroendocrine tumors: relevant clinical aspects.神经内分泌肿瘤中生长激素释放激素（GHRH）的异位分泌：相关临床方面
Ann Oncol. 2001;12 Suppl 2:S89-94. doi: 10.1093/annonc/12.suppl_2.s89.
7
Discordance between growth hormone responses after growth hormone-releasing hormone (GHRH) and insulin hypoglycemia in ectopic GHRH syndrome.异位生长激素释放激素（GHRH）综合征中生长激素释放激素（GHRH）和胰岛素低血糖后生长激素反应的不一致性。
Endocrinol Exp. 1990 Mar;24(1-2):167-73.
8
Acromegaly due to ectopic secretion of GHRH by bronchial carcinoid in a patient with empty sella.空蝶鞍患者因支气管类癌异位分泌生长激素释放激素导致的肢端肥大症。
J Endocrinol Invest. 2003 Feb;26(2):163-9. doi: 10.1007/BF03345146.
9
Humoral syndromes associated with cancer: ectopic hormone production.与癌症相关的体液综合征：异位激素产生
Prog Clin Cancer. 1982;8:57-74.
10
Acromegaly caused by ectopic growth hormone-releasing hormone secretion by a carcinoid bronchial tumor: a rare entity.由支气管类癌肿瘤异位分泌生长激素释放激素引起的肢端肥大症：一种罕见病症。
J Thorac Cardiovasc Surg. 2004 Oct;128(4):631-2. doi: 10.1016/j.jtcvs.2004.02.033.

引用本文的文献

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Paraneoplastic syndromes in lung cancer and their management.肺癌的副肿瘤综合征及其管理
Ann Transl Med. 2019 Aug;7(15):359. doi: 10.21037/atm.2019.04.86.
2
Acromegaly due to a Macroinvasive Plurihormonal Pituitary Adenoma and a Rectal Carcinoid Tumor.肢端肥大症归因于大型侵袭性多激素垂体腺瘤和直肠类癌肿瘤。
Endocrinol Metab (Seoul). 2015 Sep;30(3):389-94. doi: 10.3803/EnM.2015.30.3.389. Epub 2015 Jan 5.
3
Paraneoplastic syndromes associated with lung cancer.与肺癌相关的副肿瘤综合征。
World J Clin Oncol. 2014 Aug 10;5(3):197-223. doi: 10.5306/wjco.v5.i3.197.
4
Ectopic growth hormone-releasing hormone secretion by a bronchial carcinoid tumor: clinical experience following tumor resection and long-acting octreotide therapy.支气管类癌肿瘤异位生长激素释放激素分泌：肿瘤切除和长效奥曲肽治疗后的临床经验。
Pituitary. 2012 Jun;15(2):260-5. doi: 10.1007/s11102-010-0226-7.
5
Ectopic growth hormone-releasing hormone secretion by a metastatic bronchial carcinoid tumor: a case with a non hypophysial intracranial tumor that shrank during long acting octreotide treatment.转移性支气管类癌瘤异位分泌生长激素释放激素：一例非垂体颅内肿瘤在长效奥曲肽治疗期间缩小的病例
Pituitary. 2007;10(3):311-9. doi: 10.1007/s11102-007-0019-9.
6
Receptor imaging in the diagnosis and treatment of pituitary tumors.垂体瘤诊断与治疗中的受体显像
J Endocrinol Invest. 1999 Jan;22(1):80-8. doi: 10.1007/BF03345484.
7
Ectopic secretion of growth hormone-releasing hormone in man.人类生长激素释放激素的异位分泌
J Endocrinol Invest. 1993 Jan;16(1):69-81. doi: 10.1007/BF03345835.