Melmed S
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California.
Endocrinol Metab Clin North Am. 1991 Sep;20(3):507-18.
Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to their management is provided.
肢端肥大症可能由下丘脑肽、生长激素释放激素(GHRH)或生长激素(GH)本身的异位分泌引起。下丘脑肿瘤、类癌和胰腺肿瘤占这些病例的大多数。本文讨论了由这些非垂体肿瘤引起的肢端肥大症的发病机制、病因和诊断,并提供了其治疗方法。