Department of Clinical Physiology, Shizuoka Cancer Center Hospital, Naga-izumi, Japan.
Breast Cancer. 2010;17(1):61-7. doi: 10.1007/s12282-009-0109-9. Epub 2009 Apr 10.
A disadvantage of the image-guided core needle biopsy is that needle tract seeding may occur and affect the local recurrence and overall survival rates of patients after breast-conserving surgery, although the chance is small. The purpose of this study was to compare the potential risk of needle tract seeding of breast cancer from ultrasonographically guided needle biopsies that were performed with a directional vacuum-assisted device and an automated core needle gun.
The study compared the biopsies of 148 breast cancers performed using ultrasonographically guided core needle biopsy with the biopsies of 105 breast cancers performed using the vacuum suction probe. The potential risk of needle tract seeding of the breast cancer was defined by the cytological results derived from the needle wash material. The atypical/indeterminate, suspicious/probably malignant, and malignant categories were considered to represent positive cases.
There were significantly fewer positive cytological findings derived from the needle wash material with the directional vacuum-assisted device (33%) than with the automated core needle gun (69%) (P < 0.0001).
The use of the directional vacuum-assisted device significantly decreases the potential risk of needle tract seeding of breast cancer after an ultrasonographically guided needle biopsy.
影像引导下的核心针活检存在一个缺点，即针道种植可能发生，并影响保乳手术后患者的局部复发率和总生存率，尽管这种机会很小。本研究的目的是比较超声引导下使用定向真空辅助装置和自动活检枪进行的核心针活检对乳腺癌针道种植的潜在风险。
本研究比较了 148 例经超声引导核心针活检的乳腺癌活检和 105 例经真空抽吸探头活检的乳腺癌活检。通过针洗材料的细胞学结果来定义乳腺癌的针道种植的潜在风险。不典型/不确定、可疑/可能恶性和恶性类别被认为是阳性病例。
定向真空辅助装置（33%）获得的针洗材料阳性细胞学发现明显少于自动活检枪（69%）（P<0.0001）。
在超声引导下的核心针活检后，使用定向真空辅助装置可显著降低乳腺癌针道种植的潜在风险。
