Riggs Nathaniel R, Pentz Mary Ann
Institute for Prevention Research, Keck School of Medicine, University of Southern California, 1000 S. Fremont Avenue, Alhambra, CA 91803, USA.
Subst Use Misuse. 2009;44(5):616-31. doi: 10.1080/10826080902809691.
Evaluated were effects of a drug abuse(1) prevention program, previously shown to prevent marijuana use in adolescence, on adulthood mental health service use. Analyses were conducted on 961 6th (41%) and 7th (59%) grade participants randomly assigned to intervention or control groups at baseline in 1984. These participants were followed-up through 2003 representing 15 waves of data collection. Eighty-five percent of participants were Caucasian and 56% were female. The hypothesis was that direct program effects on early adulthood mental health service use would be mediated by program effects on high school marijuana use trajectories. Structural equation models, imputing for missing data, demonstrated that MPP (Midwestern Prevention Project) program effects on mental health were mediated by the marijuana use growth curve intercept. Findings support the role of early adolescent drug use prevention programs in impacting later mental health problems. The study's limitations are noted.
评估了一项药物滥用预防计划对成年期心理健康服务使用情况的影响，该计划此前已证明可预防青少年使用大麻。对1984年在基线时随机分配到干预组或对照组的961名六年级（41%）和七年级（59%）学生进行了分析。对这些参与者进行了随访，直至2003年，共进行了15次数据收集。85%的参与者为白人，56%为女性。假设是该计划对成年早期心理健康服务使用的直接影响将通过该计划对高中大麻使用轨迹的影响来介导。采用结构方程模型对缺失数据进行插补，结果表明，中西部预防项目（MPP）对心理健康的影响是由大麻使用增长曲线截距介导的。研究结果支持青少年早期药物使用预防计划在影响后期心理健康问题方面的作用。该研究的局限性也已指出。
