植物肽在信号传导中的作用：寻找新的伙伴。

Plant peptides in signalling: looking for new partners.

作者信息

Butenko Melinka A, Vie Ane Kjersti, Brembu Tore, Aalen Reidunn B, Bones Atle M

机构信息

Department of Molecular Biosciences, University of Oslo, N-0316 Oslo, Norway.

出版信息

Trends Plant Sci. 2009 May;14(5):255-63. doi: 10.1016/j.tplants.2009.02.002. Epub 2009 Apr 9.

DOI:10.1016/j.tplants.2009.02.002

PMID:19362511

Abstract

A novel candidate ligand-receptor system, INFLORESCENCE DEFICIENT IN ABSCISSION (IDA) and the related receptor-like kinases (RLKs) HAESA (HAE) and HAESA-LIKE (HSL)2, has been shown to control floral abscission in Arabidopsis thaliana. Furthermore, several IDA-LIKE (IDL) proteins, which contain a conserved C-terminal domain resembling that of the CLAVATA (CLV)3-ENDOSPERM SURROUNDING REGION (ESR)-RELATED (CLE) protein family, have been shown to be partially redundant with IDA. Here, we use the genetic similarities between the IDA and CLV3 signalling systems to hypothesize that closely related peptide ligands are likely to interact with families of closely related RLKs. Guided by this hypothesis and with the aid of genetics and novel methods, ligand-receptor systems can be identified to improve our understanding of developmental processes in plants.

摘要

一种新的候选配体-受体系统，即脱落缺陷花序（IDA）以及相关的类受体激酶（RLK）HAESA（HAE）和类HAESA（HSL）2，已被证明可控制拟南芥中的花器官脱落。此外，几种类IDA（IDL）蛋白，其包含一个保守的C端结构域，类似于CLAVATA（CLV）3-胚乳周围区域（ESR）相关（CLE）蛋白家族的结构域，已被证明与IDA部分冗余。在这里，我们利用IDA和CLV3信号系统之间的遗传相似性来推测，密切相关的肽配体可能与密切相关的RLK家族相互作用。在这一假设的指导下，并借助遗传学和新方法，可以识别配体-受体系统，以增进我们对植物发育过程的理解。