在子宫肌层和平滑肌瘤的单层细胞培养物中可证实存在表皮生长因子（EGF）及其受体的信使核糖核酸。
Presence of messenger ribonucleic acid for epidermal growth factor (EGF) and EGF receptor demonstrable in monolayer cell cultures of myometria and leiomyomata.
作者信息
Yeh J, Rein M, Nowak R
机构信息
Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Boston, Massachusetts 02115.
出版信息
Fertil Steril. 1991 Nov;56(5):997-1000. doi: 10.1016/s0015-0282(16)54681-0.
PMID:1936340
Abstract
There is a paucity of data concerning the factors involved in the growth of uterine leiomyomata. The expression of mRNAs encoding EGF and the EGF receptor in myometrial and leiomyoma cultures suggest that EGF may be involved in the autocrine/paracrine regulation of human uterine leiomyomata and myometrial growth.
摘要
关于子宫平滑肌瘤生长相关因素的数据匮乏。在子宫肌层和平滑肌瘤培养物中，编码表皮生长因子（EGF）及其受体的mRNA表达表明，EGF可能参与人类子宫平滑肌瘤和子宫肌层生长的自分泌/旁分泌调节。
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