Nobili C, Degrate L, Caprotti R, Franciosi C, Leone B E, Romano F, Dinelli M, Uggeri Fr
Department of Surgery, San Gerardo Hospital, University of Milano-Bicocca, via Pergolesi 33, 20052 Monza, Milano, Italy.
Gastroenterol Res Pract. 2009;2009:176793. doi: 10.1155/2009/176793. Epub 2009 Apr 12.
Sclerosing mesenteritis is a rare, idiopatic, usually benign, inflammatory process of the mesenteric adipose tissue. The most common site of involvement is the small bowel mesentery. We present a case of sclerosing mesenteritis of the rectosigmoid colon as a cause of severe abdominal pain, abdominal obstruction, and ischemic colic mucosal lesions. Contrast enema, colonoscopy, angiography, and CT were the imaging modalities used. A 20 cm diameter, fibrotic mass causing extensive compression of rectosigmoid colon was found at laparotomy. Histological examination showed extended fibrosis, inflammatory cells infiltration, lipophages, and granulomas within the mesenteric adipose tissue associated with erosive colitis. Clinical presentation and treatment are discussed.
硬化性肠系膜炎是一种罕见的、特发性的、通常为良性的肠系膜脂肪组织炎症过程。最常受累的部位是小肠系膜。我们报告一例直肠乙状结肠硬化性肠系膜炎,它是严重腹痛、肠梗阻和缺血性结肠黏膜病变的病因。使用的影像学检查方法包括钡剂灌肠、结肠镜检查、血管造影和CT。剖腹手术时发现一个直径20厘米的纤维化肿块,对直肠乙状结肠造成广泛压迫。组织学检查显示肠系膜脂肪组织内有广泛纤维化、炎症细胞浸润、噬脂细胞和肉芽肿,伴有糜烂性结肠炎。文中讨论了临床表现及治疗方法。