Park Il Ho, Kim Jae-Jin, Ku Jeonghun, Jang Hee Jeong, Park Sung-Hyouk, Kim Chan-Hyung, Kim In Young, Kim Sun I
Department of Psychiatry and the Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Korea.
Psychiatry. 2009 Spring;72(1):79-93. doi: 10.1521/psyc.2009.72.1.79.
Dysfunctional emotional processing affects social functioning in patients with schizophrenia. However, the relationship between emotional perception and response in social interaction has not been elucidated. Twenty-seven patients with schizophrenia and 27 normal controls performed a virtual reality social encounter task in which they introduced themselves to avatars expressing happy, neutral, or angry emotions while verbal response duration and onset time were measured and perception of emotional valence and arousal, and state anxiety were rated afterwards. Self-reported trait-affective scale scores and the Positive and Negative Syndrome Scale (PANSS) ratings were also obtained. Patient group significantly underestimated the valence and arousal of angry emotions expressed by an avatar. While valence and arousal ratings of happy avatars were comparable between groups, patient group reported significantly higher state anxiety in response to happy avatars. State anxiety ratings significantly decreased from encounters with neutral to happy avatars in normal controls while no significant decrease was observed in the patient group. The Social Anhedonia Scale and PANSS negative symptom subscale scores (blunted affect, emotional withdrawal, and passive/ apathetic social withdrawal items) were significantly correlated with state anxiety ratings of the encounters with happy avatars. These results suggest that patients with schizophrenia have interference with the experience of pleasure in social interactions which may be associated with negative symptoms.
功能失调的情绪加工会影响精神分裂症患者的社交功能。然而，社交互动中情绪感知与反应之间的关系尚未阐明。27名精神分裂症患者和27名正常对照者进行了一项虚拟现实社交遭遇任务，在该任务中，他们向表现出高兴、中性或愤怒情绪的虚拟化身自我介绍，同时测量言语反应持续时间和起始时间，并在之后对情绪效价和唤醒水平的感知以及状态焦虑进行评分。还获取了自我报告的特质情感量表分数和阳性与阴性症状量表（PANSS）评分。患者组显著低估了虚拟化身所表达愤怒情绪的效价和唤醒水平。虽然两组对高兴虚拟化身的效价和唤醒水平评分相当，但患者组报告称，对高兴虚拟化身的反应中状态焦虑显著更高。在正常对照者中，从与中性虚拟化身的遭遇至与高兴虚拟化身的遭遇，状态焦虑评分显著降低，而在患者组中未观察到显著降低。社交快感缺乏量表和PANSS阴性症状分量表分数（情感迟钝、情感退缩以及被动/淡漠社交退缩项目）与对高兴虚拟化身遭遇的状态焦虑评分显著相关。这些结果表明，精神分裂症患者在社交互动中的愉悦体验存在干扰，这可能与阴性症状有关。
