Papenfort Kai, Vogel Jörg
Max Planck Institute for Infection Biology, RNA Biology Group, Charitéplatz 1, 10117 Berlin, Germany.
Res Microbiol. 2009 May;160(4):278-87. doi: 10.1016/j.resmic.2009.03.004. Epub 2009 Apr 12.
Small noncoding RNAs (sRNAs), often in conjunction with Hfq protein, have increasingly been shown to regulate multiple rather than individual mRNAs, thereby reprogramming gene expression at the post-transcriptional level. This review summarizes how and when several such regulators (CyaR, DsrA, GcvB, OmrAB, RNAIII, RybB, RyhB) act upon multiple targets.
小非编码RNA（sRNA）通常与Hfq蛋白协同作用，越来越多的研究表明，它可调控多个而非单个mRNA，从而在转录后水平对基因表达进行重编程。本综述总结了几种此类调控因子（CyaR、DsrA、GcvB、OmrAB、RNAIII、RybB、RyhB）作用于多个靶标的方式和时间。
