Maraspin Vera, Strle Franc
Curr Probl Dermatol. 2009;37:183-190. doi: 10.1159/000213076. Epub 2009 Apr 8.
In this report, we present basic data pertinent to the current understanding of borrelial infection in pregnancy, and propose a rationale for the management of Lyme borreliosis in pregnant women. We advocate early detection of attached ticks and their prompt removal. We do not recommend the use of prophylactic antibiotics in pregnant women but support the 'wait and watch' strategy, including early treatment with antibiotics if signs/symptoms of the disease arise. We encourage the approach that antibiotic treatment of pregnant patients is restricted to those having a reliable clinical diagnosis of Lyme borreliosis, and propose intravenous antibiotic treatment with penicillin, or preferably ceftriaxone 2 g daily for 14 days, not only for patients with early disseminated disease but also for those with solitary erythema migrans.
在本报告中，我们提供了与当前对妊娠期疏螺旋体感染的理解相关的基础数据，并提出了孕妇莱姆病疏螺旋体病管理的基本原理。我们提倡早期发现附着的蜱虫并及时清除。我们不建议孕妇使用预防性抗生素，而是支持“观察等待”策略，包括如果出现疾病体征/症状则尽早使用抗生素治疗。我们鼓励采取的方法是，孕妇的抗生素治疗仅限于那些有可靠的莱姆病疏螺旋体病临床诊断的患者，并建议静脉注射青霉素进行抗生素治疗，或者优选每日2克头孢曲松，持续14天，不仅适用于早期播散性疾病患者，也适用于单发游走性红斑患者。
